Professional Training

Early Stage Upstream Process Development

PTI, Online
4 weeks
4 weeks
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Course description

Early Stage Upstream Process Development

Upstream processing refers to the first phase in biomolecule production. This process involves a series of intricate steps which must be carefully followed to ensure a successful transition to downstream processing.

Over the course of 5 weeks this course will walk you through the basics of early-stage upstream process development for mammalian and microbial products. The course will focus on USP planning, cell-line development, media selection and will finish with quality considerations to help you lay the foundations for a successful and productive bioprocess.

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Suitability - Who should attend?

This course will be of interest to all professionals involved in upstream process development, including:

  • Process scientists
  • Technicians and technologists
  • Bioprocess engineers
  • Cell line development specialists
  • Cell culture specialists
  • Product managers
  • Process development managers
  • Quality assurance specialists
  • Validation technicians
  • Managers

Outcome / Qualification etc.

  • Understand processes involved with cell-line development including requirements, stability studies and vector design
  • Consider selection of media for different production strategies, testing and characterisation, viral and GMP concerns
  • Gain a comprehensive understanding of the initial upstream development process
  • Familiarise yourself with key quality considerations such as quality by design, experimental design and risk management

Training Course Content

  • Module 1: Introduction
  • Module 2: Cell-line development
  • Module 3: Media selection
  • Module 4: Initial upstream process development
  • Module 5: Quality considerations

Why choose PTI

On average, delegates of their online academies said: 

Quality of content:


85% had applied content during the course to their role

Delivery rating:


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