Course description
The aims of this course are to investigate how procaryotic and eucaryotic genomes are sequenced, constructed and annotated; and how the genomes from different classes of organism are compared; and to demonstrate the potential commercial exploitation of such genomic analysis.
Course content
•Aspects of the genomics of bacteria, viruses, yeast and fungi.
•Sequencing genomes: contig construction, genome completion, genome annotation.
•Comparative microbial genomics– microbial circular and line argenomes, mega- plasmids, reduced genomes– using a range of case studies.
•Diversity and phylogenetic relationships: 16S rDNA sequencing and other conserved sequences; cluster analysis; phylogenetic tree construction.
•Community DNA analysis, metagenomics, identification of uncultured organisms.
•Location of core genes for metabolism; virulence.
•Analysis of metabolic pathways, structure and function using KEGG.
Assessment will comprise an investigation of sequence data using bioinformatics databases, and a critique of the findings (100%).
Do you work at this organisation and want to update this page?
Is there out-of-date information about your organisation or courses published here? Fill out this form to get in touch with us.